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patients should be made aware that wellbutrin contains the same active ingredient found in zyban, used as an aid to smoking cessation treatment, and that wellbutrin should not be used in combination with zyban, or any other medications that contain bupropion, such as wellbutrin sr bupropion hydrochloride , the sustained-release formulation or wellbutrin xl bupropion hydrochloride , the extended-release formulation.

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, wellbutrin xl 300 mg once daily was shown to have bioavailability that was similar to that of 100 mg 3 times daily of the immediate-release formulation of bupropion and to that of 150 mg 2 times daily of the sustained-release formulation of bupropion, with regard to both peak plasma concentration and extent of absorption, for parent drug and metabolites.

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wellbutrin xl bupropion is a prescription antidepressant used to treat major depressive disorder and seasonal affective disorder.

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