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Since cq and its derivatives are the only inhibitors of autophagy that are available for use in the clinic, multiple ongoing clinical trials are currently using cq or hydroxychloroquine hcq for this purpose, either alone, or in combination with other anticancer drugs.

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chloroquine diphosphate has been reported as an adjuvant for radiation and chemotherapy for inducing cell autophagy to anti-cancer cells proliferation or metastasis 2 .

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chloroquine is used in some people to help reduce the damage these conditions can cause.
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Amodiaquine is a 4-aminoquinolone anti-malarial drug similar in structure and mechanism of action to chloroquine.

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