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No dedicated pharmacokinetic study alli weight loss reviews forums. has been conducted using colchicine capsules in patients with varying degrees of renal impairmentColchicine is known to be excreted in urine in humans and the presence of severe renal impairment has been associated with colchicine toxicityUrinary clearance of colchicine and its metabolites may be decreased in patients with impaired renal functionDose reduction or alternatives should be considered for the prophylaxis of gout flares in patients with severe renal impairmentColchicine is not effectively removed by hemodialysisPatients who are undergoing hemodialysis should be monitored carefully for colchicine toxicity.

If you are taking colchicine to treat FMFyour doctor may start you on a low dose and gradually increase your doseYour doctor may decrease your dose if you experience side effects.

Read the Medication Guide provided by your pharmacist before you start taking colchicine and each time you get a refillIf you have any questions regarding the informationask your doctor or pharmacist.

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