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Drugs which induce cytochrome P450 3A4CYP 3A4enzyme viagra effects on women. activitye.gbarbituratesphenytoincarbamazepinerifampinmay enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increasedDrugs which inhibit CYP 3A4e.gketoconazolemacrolide antibiotics such as erythromycinhave the potential to result in increased plasma concentrations of corticosteroidsDexamethasone is a moderate inducer of CYP 3A4Co-administration with other drugs that are metabolized by CYP 3A4e.gindinavirerythromycinmay increase their clearanceresulting in decreased plasma concentration.

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Administration of live or liveattenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids.

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