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Check for contraindications to the administration of isoniazid for preventive therapy.
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tasimelteon major concurrent use of tasimelteon and strong inhibitors of cyp3a4, such as isoniazid, inh, should be avoided if possible.
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calcium channel blockers eg, verapamil , corticosteroids eg, prednisone , diuretics eg, hydrochlorothiazide , estrogen, isoniazid, nicotinic acid, oral contraceptives birth control pills , phenothiazines eg, chlorpromazine , phenytoin, sympathomimetics eg, pseudoephedrine , or thyroid hormone as they may decrease the expected effectiveness of precose.
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liver function should be checked before treatment with isoniazid and special care should be taken in alcoholic patients or those with pre-existing liver disease.
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In conclusion, this outpatient-based comparison of four months of rifampin, three months of isoniazid and rifapentine, and nine months of isoniazid demonstrates comparable completion rates between four months of rifampin and three months of isoniazid and rifapentine while taking into consideration the monitoring frequency.
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