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In patients with normal renal function or mild to moderate renal insufficiencylinezolid is primarily excreted under steady-state conditions in the urine as PNU-14258640parent drug30and PNU-14230010Virtually no parent drug is found in the faeces whilst approximately 6and 3of each dose appears as PNU-142586 and PNU-142300respectivelyThe elimination half-life of linezolid averages at about 5-7 hours.
FDA pregnancy category CIt is not known whether linezolid is harmful to an unborn babyTell your doctor if you are pregnant or plan to become pregnant during treatment.
Community-acquired pneumonia caused by Streptococcus pneumoniaeincluding cases with concurrent bacteremiaor Staphylococcus aureusmethicillin-susceptible strains only
Diarrhoeanauseavomitinglocalised or general abdominal painconstipationdyspepsia.
It is unknown if this drug passes into breast milkConsult your doctor before breast-feeding.
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