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John s wort because they may decrease calan s effectiveness aldosterone blockers eg, eplerenone , aspirin, carbamazepine, colchicine, cyclosporine, digoxin, dofetilide, doxorubicin, dronedarone, eletriptan, erythromycin, everolimus, flecainide, hmg-coa reductase inhibitors eg, lovastatin, simvastatin , lithium, narcotic pain relievers eg, fentanyl , paclitaxel, quinazolines eg, terazosin , quinidine, ranolazine, theophyllines, or tolvaptan because the risk of their side effects may be increased by calan.

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