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Using the same technique, we also found an increase in hdac2 gene transcription in response to repeated fluoxetine administration; the most pronounced effect took place in the striatum table 1 , thus confirming the increase in hdac2 labeling intensity we observed immunohistochemically.

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due to the risk of serious ventricular arrhythmias and sudden death potentially associated with elevated plasma levels of thioridazine, thioridazine should not be administered with fluoxetine or within a minimum of 5 weeks after fluoxetine has been discontinued see contraindications 4 .


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