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The liver metabolizes methotrexate and later it is excreted in the urine.

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Methotrexate is usually given after other medications have been tried without successful treatment of symptoms.

Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.

Methotrexate can be toxic to your organsand may lower your blood cell countsYour blood will need to be tested oftenand you may canadianpharmacywithoutprescription. need an occasional liver biopsyYour cancer treatments may be delayed based on the results.

Single Dose10 to 25 mg/week orallyIMor IV until adequate response is achievedDivided Dose2.5 mg orallyIMor IV every 12 hours for 3 doses once a weekMaximum weekly dose30 mg.

Get medical help right away if you have any very serious side effectsincludingweakness on one side of the bodyneck stiffnesssevere headachevision changesirregular heartbeatmental/mood changesseizures.

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