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During this four-month phase, normally only isoniazid and rifampicin the two most powerful first-line drugs are taken on a daily basis.

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for isoniazid-resistant strains in hiv-infected patients, guidelines suggest rifampin or rifabutin plus ethambutol, pyrazinamide, and a quinolone levofloxacin moxifloxacin for the first 2 months, then rifampin or rifabutin , ethambutol, and a quinolone levofloxacin moxifloxacin for 7 months.

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rifampin moderate careful monitoring of hepatic function is recommended with the concurrent use of isoniazid, inh and rifampin.


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