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In harmonising the contraindicationsthe CHMP decided against including two contraindications that were in the SmPCs of some EU countriesliver impairment and pre-operative use in patients whose receptor status is negative or unknownThe CHMP was of the view that it was more appropriate to include relevant warnings in section 4.4.
The optimal duration of treatment with Femara is not knownTreatment should be discontinued if there is a tumor relapse.
Some patients taking FEMARA had an increase in cholesterolYour doctor may require the monitoring of cholesterol in your blood.
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the frequencies of adverse reactions for femara are mainly based on data collected from clinical trials.