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We now report an additional way of predefining patients likely to respond to naltrexone by using fmri to measure patients brain activity in response to alcohol cues versus neutral cues.

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Safe use of REVIA in ultra rapid opiate detoxification programs has not been establishedsee ADVERSE REACTIONS

Naltrexone may cause liver damage when taken in large dosesIt is not likely that naltrexone will cause liver damage when taken in recommended dosesTell your doctor if you have or have ever had hepatitis or liver diseaseIf you experience any of the following symptomsstop taking naltrexone and call your doctor immediatelyexcessive tiredness,unusual bleeding or bruisingloss of appetitepain in the upper right part of your stomach that lasts more than a few dayslight-colored bowel movements,dark urineor yellowing of the skin or eyes.

Clinicians are reminded that there is no completely reliable method for determining whether a patient has had an adequate opioid-free periodA naloxone challenge test may be helpful if there is any question of occult opioid dependenceIf signs of opioid withdrawal are still observed following naloxone challengetreatment with REVIA should not be attemptedThe naloxone challenge can be repeated in 24 hours.

Patients with addictive disordersespecially opioid addictionare at risk for multiple numerous adverse events and abnormal laboratory findingsincluding liver function abnormalitiesData from both controlled and observational studies suggest that these abnormalitiesother than the dose-related hepatotoxicity described aboveare not related to the use of REVIA.

Naltrexone is used along with counseling and social support to help people who have stopped drinking hydrochlorothiazide 25 mg picture. alcohol and using street drugs continue to avoid drinking or using drugsNaltrexone should not be used to treat people who are still using street drugs or drinking large amounts of alcoholNaltrexone is in a class of medications called opiate antagonistsIt works by decreasing the craving for alcohol and blocking the effects of opiate medications and opioid street drugs.

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