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Estrogen therapy may cause an exacerbation of asthmadiabetes mellitusepilepsymigraineporphyriasystemic lupus erythematosusand hepatic hemangiomas and should be used with caution in women with these conditions.
Premarin may increase your risk of developing a condition that may lead to uterine cancerYour doctor may prescribe a progestin to take while you are using Premarinto help lower this riskReport any unusual vaginal bleeding right away.
Since large and repeated doses of estrogen over an extended time period have been shown to accelerate epiphyseal closurehormonal therapy should not be started before epiphyseal closure has occurred in order not to compromise final growth.
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