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3Endometriosis and Endometrial CarcinomaThe incidence of endometriosis and endometrial carcinoma increases with age as does the incidence of ovulatory disordersEndometrial biopsy should always be performed prior to clomiPHENE citrate therapy in this population.

Clomid works by blocking estrogen receptors in the hypothalamus and pituitary glandThe result is that the pituitary gland is stimulated to produce more of the hormones that cause eggs to develop in the ovariesThese hormones are called gonadotropins and there are two important onesFSH or follicle stimulating hormone and LH or luteinizing hormoneDuring clomid treatmentthe levels of LH and FSH both increaseIt is the FSH that is initially more important to get eggs to develop.

In the event of overdoseappropriate supportive measures should be employed in addition to gastrointestinal decontamination.

2Patients without ovarian cystsClomiPHENE citrate should not be used in patients with ovarian enlargement except in those with polycystic ovary syndromePelvic examination is necessary prior to the first and each subsequent course of clomiPHENE citrate treatment.

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stop taking serophene and seek emergency medical attention if you experience an allergic reaction difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives .