A events considered to be dose dependent are defined as events having an incidence rate with 25 mg of paroxetine hydrochloride controlled-release tablets that was at least twice that with 12.
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based on the mechanism of action of paroxetine and the potential for serotonin syndrome, caution is advised when paroxetine is coadministered with other drugs or agents that may affect the serotonergic neurotransmitter systems, such as triptans, linezolid an antibiotic which is a reversible non-selective maoi , lithium, fentanyl, tramadol, amphetamines, or st.
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in 2004, the canadian medical association journal described a leaked document indicating that glaxosmithkline had deliberately hidden two studies from regulators showing that its antidepressant, paxil paroxetine , could increase the risk of suicide in children.
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discontinuation is similar in nature, but not identical to those of ssris such as paroxetine paxil or seroxat.
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