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Before initiating treatment with SINEMETadvise patients about the potential to develop drowsiness and ask specifically about factors that may increase the risk for somnolence with SINEMET such as the use of concomitant sedating medications and the presence of sleep disordersConsider discontinuing SINEMET in patients who report significant daytime sleepiness or episodes of falling asleep during activities that require active participatione.gconversationseatingetcIf treatment with SINEMET continuespatients should be advised buy oxycontin mexico pharmacy. not to drive and to avoid other potentially dangerous activities that might result in harm if the patients become somnolentThere is insufficient information to establish that dose reduction will eliminate episodes of falling asleep while engaged in activities of daily living.

These are all serious side effects that need urgent medical attentionSerious side effects are generally rare.

These are all serious side effects that need urgent medical attentionSerious side effects are generally rare.

Sporadic cases of hyperpyrexia and confusion have been associated with dose reductions and withdrawal of SINEMETPatients should be observed carefully if abrupt reduction or discontinuation of SINEMET is requiredespecially if the patient is receiving neurolepticsSee WARNINGS

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