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In preclinical studies in rats and dogs, renagel at a dose of 10 times the maximum human doses reduced absorption of fat soluble vitamins d, e and k, and folic acid.

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this multicenter, open-label, dose-titration study assessed the safety and efficacy of renagel , a nonabsorbed calcium- and aluminum-free phosphate binder, in lowering serum phosphorus.

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the first study compared renagel with calcium acetate another.


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