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2007 mutations in transmembrane domains 1, 4 and 9 of the plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.
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In some embodiments, the serpina-1 polypeptide comprises the amino acid sequence set forth as edpqgdaaqktdtshhdqdhptfnkitpnlaefafs seq id no 4 .
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