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If you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have a history of diabetes, an underactive thyroid, heart problems, gallbladder problems eg, gallstones , pancreatitis, kidney or liver problems, or muscle problems if you have a history of blood clots in your veins deep vein thrombosis or pulmonary embolism if you are very overweight, have an inactive lifestyle, have a poor diet, or you drink alcohol or have a history of alcohol abuse if you have trouble swallowing if you are taking a beta-blocker eg, propranolol , estrogen, or thiazide diuretic eg, hydrochlorothiazide .
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Propranolol also is produced as a generic product by a number of generic manufacturers.
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The pill contraceptive certain antibiotics such as erythromycin , clarithromycin , fluoroquinolones and ciprofloxacin verapamil, diltiazem medicines for heart rhythm disturbances propranolol remedy the blood thinner ticlopidine cimetidine and ranitidine agent for stomach problems gout agent allopurinol and febuxostat acyclovir remedy for herpes .
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Use propranolol with caution in patients with renal impairment because decreased plasma clearance may occur.
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However, one complication is that propranolol, like many other b-adrenoceptor antagonists, is also a 5-ht1a receptor antagonist which could contribute to its anti-anxiety effects see below .
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